Linked Life Data

3169589

Source:http://linkedlifedata.com/resource/pubmed/id/3169589

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-11-15
pubmed:abstractText
Homoharringtonine, an alkaloid indigenous to China, was studied for its effect on fibroblast growth in cell culture and on intraocular proliferation produced in rabbits by injecting homologous fibroblasts into the vitreous. The results demonstrate that homoharringtonine reduced the cell growth by 50% at a concentration of 0.005 mg/l in vitro, significantly inhibited vitreous proliferation, and prevented the occurrence of retinal detachment in vivo. Light and electron microscopy revealed no ocular toxicity in drug-treated eyes. Homoharringtonine may be of considerable value in the prevention and treatment of intraocular proliferation in patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0721-832X
pubmed:author
pubmed:issnType
Print
pubmed:volume
226
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
367-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Inhibition of intraocular proliferation by homoharringtonine. An experimental study.
pubmed:affiliation
Department of Ophthalmology, Union Hospital, Tongji Medical University, Wuhan, People's Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't