Linked Life Data

3161822

Source:http://linkedlifedata.com/resource/pubmed/id/3161822

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-10-9
pubmed:abstractText
The role of the A and E molecules as restriction elements was examined in the F antigen system. In the mouse the only responder haplotype known to date is k, and blocking studies with a monoclonal antibody show that in vitro T-cell proliferation is restricted by the Ak molecule. The (CBA X DBA/2)F1 hybrid, which is a responder X nonresponder cross, is itself a nonresponder in terms of F-specific antibody production. Up to 10 days after priming, (CBA X DBA/2)F1 T cells exhibited an F-specific proliferative response, but this diminished rapidly at later times. This diminution could be blocked with an E-specific monoclonal antibody, suggesting that suppression is restricted by the E molecule.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0093-7711
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-75
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
T helper and T suppressor cells are restricted by the A and E molecules, respectively, in the F antigen system.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't