rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1985-9-19
|
pubmed:abstractText |
To assess the validity of serum dehydroepiandrosterone sulphate (DS) radioimmunoassay instead of urinary total 17-ketosteroid (17-KS) or individual metabolite (dehydroepiandrosterone + etiocholanolone + androsterone; D + E + A) determination to control adrenal androgen function, a comparative study has been performed. Mathematical analysis of simultaneous estimates revealed significant correlation when normal or above normal 17-KS or D + E + A excretion relative to serum DS were considered. Poor correlation was observed when below normal metabolite excretion and serum DS were related. Furthermore, there was a significant correlation between estimates of 17-KS (or D + E + A) and those of serum unconjugated D also determined by radioimmunoassay. The serum DS radioimmunoassay appeared to be a reliable tool to assess adrenal androgen function, at least in patients exhibiting normal or high 17-ketosteroid values.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0232-7384
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
85
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
209-16
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3160599-17-Ketosteroids,
pubmed-meshheading:3160599-Adolescent,
pubmed-meshheading:3160599-Adrenal Glands,
pubmed-meshheading:3160599-Adult,
pubmed-meshheading:3160599-Aged,
pubmed-meshheading:3160599-Androgens,
pubmed-meshheading:3160599-Androsterone,
pubmed-meshheading:3160599-Dehydroepiandrosterone,
pubmed-meshheading:3160599-Dehydroepiandrosterone Sulfate,
pubmed-meshheading:3160599-Etiocholanolone,
pubmed-meshheading:3160599-Female,
pubmed-meshheading:3160599-Humans,
pubmed-meshheading:3160599-Male,
pubmed-meshheading:3160599-Middle Aged,
pubmed-meshheading:3160599-Radioimmunoassay
|
pubmed:year |
1985
|
pubmed:articleTitle |
Relationship between serum dehydroepiandrosterone sulphate and urinary 17-ketosteroid values.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|