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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1985-8-1
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pubmed:abstractText |
A case of fatal hepato-renal failure occurring during mithramycin treatment is reported. A 64 year-old female patient was admitted to hospital in a state of acute renal failure. She also presented with hypercalcaemia and bilateral pulmonary metastases. She had been operated on 10 years previously of a parathyroid cancer. Despite treatment with mithramycin (total dose 8.25 mg) and haemodialysis, the hypercalcaemia returned; it was then decided to remove the secretory lung metastases (parathormone 420 micrograms X ml-1). 48 hours before surgery, the patient was again given 1.25 mg mithramycin. Immediately after surgery, she developed hepatic failure with massive cell destruction and anuria. The patient died 48 h after the operation. The hepatic and renal complications of mithramycin are discussed.
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pubmed:language |
fre
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0750-7658
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-3
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:3160268-Acute Kidney Injury,
pubmed-meshheading:3160268-Calcium,
pubmed-meshheading:3160268-Creatinine,
pubmed-meshheading:3160268-Drug-Induced Liver Injury,
pubmed-meshheading:3160268-Female,
pubmed-meshheading:3160268-Humans,
pubmed-meshheading:3160268-Hypercalcemia,
pubmed-meshheading:3160268-Middle Aged,
pubmed-meshheading:3160268-Parathyroid Neoplasms,
pubmed-meshheading:3160268-Plicamycin
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pubmed:year |
1985
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pubmed:articleTitle |
[Acute fatal hepatorenal failure during treatment with mithramycin].
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|