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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
5
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pubmed:dateCreated |
1985-8-5
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pubmed:abstractText |
A true hermaphrodite with a bilateral ovotestis and a 46 XX karyotype was studied. This 14-year old subject developed ambiguous puberty with bilateral gynecomastia and stage IV public hair. Relatively high level of testosterone (T) (2.80 ng/ml), was found. The 5 alpha-reductase activity for T in the pubic skin was similar to that observed in normal adult males. A hemorrhagic corpus luteum in the left ovotestis was observed at laparotomy. The luteal phase immediately after dexamethasone administration (1 mg/day for 7 days) was characterized by a significant decrease of plasma androgens, T and androstenedione (A). The constantly low level of T (0.30 ng/ml) during the luteal phase in this subject did not appear to be due to the previously administered dexamethasone. This decrease of T production in the luteal phase might be secondary either to the increase of the estradiol-17 beta (E2) secreted by the corpus luteum or to the decrease of LH levels. Both mechanisms might act concomitantly.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-4731
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
631-4
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:3159938-Adolescent,
pubmed-meshheading:3159938-Androgens,
pubmed-meshheading:3159938-Androstenedione,
pubmed-meshheading:3159938-Cosyntropin,
pubmed-meshheading:3159938-Dehydroepiandrosterone,
pubmed-meshheading:3159938-Dexamethasone,
pubmed-meshheading:3159938-Disorders of Sex Development,
pubmed-meshheading:3159938-Female,
pubmed-meshheading:3159938-Follicle Stimulating Hormone,
pubmed-meshheading:3159938-Genitalia, Male,
pubmed-meshheading:3159938-Humans,
pubmed-meshheading:3159938-Karyotyping,
pubmed-meshheading:3159938-Luteal Phase,
pubmed-meshheading:3159938-Luteinizing Hormone,
pubmed-meshheading:3159938-Male,
pubmed-meshheading:3159938-Ovary,
pubmed-meshheading:3159938-Radioimmunoassay,
pubmed-meshheading:3159938-Testis,
pubmed-meshheading:3159938-Testosterone
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pubmed:year |
1985
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pubmed:articleTitle |
Plasma androgens during the luteal phase in a case of true hermaphroditism with bilateral ovotestis.
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pubmed:publicationType |
Journal Article,
In Vitro,
Case Reports
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