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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1985-6-6
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pubmed:abstractText |
To determine whether the frequency of chronic hepatitis B in homosexual men reflects the high rate of acute hepatitis B or an altered response to hepatitis B, 236 homosexual men were prospectively followed up after entry into the placebo group of a hepatitis B vaccine trial. Sixty-six participants (28.0%) developed hepatitis B ten to 18 months after entering the study. Only four (6.1%) of the 66 had persistence of hepatitis B beyond six months, similar to reports in nonhomosexual subjects. This study suggests that the high rate of acute hepatitis B is the major factor contributing to the high prevalence of chronic hepatitis B in homosexual men, rather than an altered host response. Clinical features of the acute illness could not be used to identify patients who developed chronic hepatitis B.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0003-9926
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
881-2
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3158291-Acute Disease,
pubmed-meshheading:3158291-Adolescent,
pubmed-meshheading:3158291-Clinical Trials as Topic,
pubmed-meshheading:3158291-Double-Blind Method,
pubmed-meshheading:3158291-Hepatitis, Chronic,
pubmed-meshheading:3158291-Hepatitis B,
pubmed-meshheading:3158291-Hepatitis B Vaccines,
pubmed-meshheading:3158291-Homosexuality,
pubmed-meshheading:3158291-Humans,
pubmed-meshheading:3158291-Male,
pubmed-meshheading:3158291-Placebos,
pubmed-meshheading:3158291-Prospective Studies,
pubmed-meshheading:3158291-Random Allocation,
pubmed-meshheading:3158291-Viral Hepatitis Vaccines
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pubmed:year |
1985
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pubmed:articleTitle |
Evolution of acute hepatitis B in homosexual men to chronic hepatitis B. Prospective study of placebo recipients in a hepatitis B vaccine trial.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|