Linked Life Data

3157802

Source:http://linkedlifedata.com/resource/pubmed/id/3157802

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-5-30
pubmed:abstractText
Nine patients with the acquired immunodeficiency syndrome (AIDS) were studied for suppressor cell activity utilizing an allogeneic mixed lymphocyte culture technique. The patients studied had opportunistic infections and a high incidence of intravenous drug abuse. T lymphocytes of the AIDS patients showed a consistently greater ability to suppress immunoglobulin M (IgM) synthesis by pokeweed mitogen stimulated allogeneic lymphocytes compared to controls (p less than 0.03). In 4 patients, T helper function was studied and compared to controls. Diminished helper cell function was consistently observed (p less than 0.01). All AIDS patients had leu 3a/leu 2a ratios of less than 0.9. However, a statistical correlation between the helper/suppressor cell ratio and suppressor activity was not demonstrated. Functional tests of T lymphocytes may be of value in assessing immunocompetence in patients with altered lymphocyte subset ratios.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0141-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Suppressor function of T lymphocytes in the acquired immunodeficiency syndrome as assessed by allogeneic mixed lymphocyte culture.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro