Linked Life Data

3157727

Source:http://linkedlifedata.com/resource/pubmed/id/3157727

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-6-18
pubmed:abstractText
The purpose of this study was to demonstrate the approach of using the degree of familial aggregation to validate a subtype of affective illness. In order to determine whether clinical response to pharmacological therapy in the proband treated for non-bipolar major depression constitutes a distinct subtype of depression, rates of affective illness were examined among relatives of probands who were categorized according to the speed and magnitude of their response to somatic treatment in controlled clinical trials. First-degree relatives of probands who experienced rapid improvement during the first week and poor response on termination of treatment, were found to have the highest rates of major depression. These results require replication.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0165-0327
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-6
pubmed:dateRevised
2009-9-28
pubmed:meshHeading
pubmed:articleTitle
Drug response as a predictor of transmission of non-bipolar major depression within families.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S.