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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-4-26
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pubmed:abstractText |
The phenotypic and functional characteristics of the leukemic cells from one patient with a suppressor T-ALL were studied. At the time of diagnosis a high proportion of OKT8 positive (suppressor/cytotoxic) cells were identified which mediated strong suppressor activity to the differentiation of allogenic B-cells. A complete remission of 12 months duration was achieved by chemotherapy. In the relapse the marker analysis showed a dramatic decrease of the OKT8 positive cell fraction. Functionally the suppressor activity was completely lost indicating a close correlation between phenotype and functional activity also in a leukemic cell population.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0340-1162
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3156806-Adult,
pubmed-meshheading:3156806-Antibodies, Monoclonal,
pubmed-meshheading:3156806-B-Lymphocytes,
pubmed-meshheading:3156806-Humans,
pubmed-meshheading:3156806-Leukemia, Lymphoid,
pubmed-meshheading:3156806-Leukocyte Count,
pubmed-meshheading:3156806-Male,
pubmed-meshheading:3156806-T-Lymphocytes,
pubmed-meshheading:3156806-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:3156806-T-Lymphocytes, Regulatory
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pubmed:year |
1985
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pubmed:articleTitle |
[Characterization of the leukemic cell population in a patient with T-ALL at disease beginning and in recurrence: parallel changes in phenotypic and functional behavior].
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pubmed:publicationType |
Journal Article,
English Abstract
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