Linked Life Data

3154528

Source:http://linkedlifedata.com/resource/pubmed/id/3154528

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-4-5
pubmed:abstractText
Neuroendocrine and mood responses to a 60 mg oral dose of the serotonin-releasing agent, fenfluramine, were assessed in ten neuroleptic-free, chronic schizophrenic patients and in age- and sex-matched normal control subjects. The prolactin (PRL) response to fenfluramine was significantly blunted in the schizophrenic subjects. Growth hormone and cortisol levels were not differentially affected by the challenge. There was no significant effect of fenfluramine on mood in either group. The blunted PRL response in the schizophrenic group suggests serotonergic dysfunction; possible mechanisms of this finding and implications for treatment are considered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0920-9964
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-10
pubmed:dateRevised
2010-9-2
pubmed:meshHeading
pubmed:articleTitle
Neuroendocrine responses in chronic schizophrenia. Evidence for serotonergic dysfunction.
pubmed:affiliation
Jerusalem Mental Health Center-Ezrath Nashim Hospital, Israel.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't