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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1980-1-19
|
| pubmed:abstractText |
The mean sodium current, I, and the variance of sodium current fluctuations, var, were measured in myelinated nerve during a depolarization to V = 40 mV applied from the resting potential (VH = 0) or from a hyperpolarizing holding potential VH = -28 mV. From I and var the relative variations in the number N and the conductance gamma of sodium channels following changes of the holding potential were calculated. Hyperpolarizing the membrane from VH = 0 to -28 mV increased N by a factor of 3.7, whereas gamma decreased by a factor of 0.53. These actions of holding potential on sodium channels develop slowly since 500 ms prepulses to 0 or -28 mV do not alter the values of N and gamma.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0006-3002
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
16
|
| pubmed:volume |
558
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
113-8
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:315238-Animals,
pubmed-meshheading:315238-Anura,
pubmed-meshheading:315238-Cell Membrane,
pubmed-meshheading:315238-Ion Channels,
pubmed-meshheading:315238-Mathematics,
pubmed-meshheading:315238-Membrane Potentials,
pubmed-meshheading:315238-Myelin Sheath,
pubmed-meshheading:315238-Peripheral Nerves,
pubmed-meshheading:315238-Rana esculenta,
pubmed-meshheading:315238-Sodium
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Slow actions of hyperpolarization on sodium channels in the membrane of myelinated nerve.
|
| pubmed:publicationType |
Journal Article
|