Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-5-22
pubmed:abstractText
The intensity and distribution of histochemically demonstrable dihydrofolate reductase (FH2-R EC 1.5.1.3.) in unfixed cryostat sections was studied in Purkinje neurons of adult vertebrates that have either simple neural circuits and cytoarchitectonics (Ictalurus nebulosus, Rana esculenta) or complex neural circuits and cytoarchitectonics (Coturnix coturnix japonica), compared with the rat as a control. The reaction was generally undetectable in Ictalurus nebulosus and in Rana esculenta; with positive reactions in only a few neurons. On the contrary, FH2-R in the Purkinje cell population of Coturnix coturnix japonica had several pattern (heterogeneity) as in the rat. These results suggest that the existence of FH2-R in Purkinje cell population may be correlated with the complexity of the neural circuits of the vertebrate's cerebellum and that the "heterogeneity" of the reaction may be related to the different functional states of the Purkinje cells within the cerebellum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-1281
pubmed:author
pubmed:issnType
Print
pubmed:volume
84
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Dihydrofolate reductase activity in the Purkinje neuron populations of some non-mammalian vertebrates.
pubmed:affiliation
Department of Animal Biology, University of Pavia, Italy.
pubmed:publicationType
Journal Article, Comparative Study