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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1989-3-16
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pubmed:abstractText |
The diagnostic value of detection of specific IgM antibodies was analysed in Mycoplasma pneumoniae infections. In a retrospective clinical and serological study, M. pneumoniae IgM antibodies were determined by a mu-capture ELISA using enzyme-labelled antigen. The study group consisted of 91 patients with significantly raised titers in paired sera or a single high titer of complement fixation antibodies. About 40% of the patients had been treated with antibiotics ineffective against M. pneumoniae infections prior to admission to hospital. Treatment with erythromycin or tetracycline was shown to give a shorter period of fever compared to if no or ineffective therapy was given. Specific IgM antibodies were detected in about 80% of sera sampled 9 days or more after onset of symptoms. In sera sampled at 7-8 days after onset IgM antibodies were found in about 40% of the sera but only occasionally in sera sampled earlier. In the age group 0-20 years 88% of the patients developed an IgM response. In the higher ages (greater than 60 years) a significantly lower rate of IgM responders was observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-10
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3146809-Adolescent,
pubmed-meshheading:3146809-Adult,
pubmed-meshheading:3146809-Age Factors,
pubmed-meshheading:3146809-Antibodies, Bacterial,
pubmed-meshheading:3146809-Antibody Specificity,
pubmed-meshheading:3146809-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:3146809-Erythromycin,
pubmed-meshheading:3146809-Humans,
pubmed-meshheading:3146809-Immunoglobulin M,
pubmed-meshheading:3146809-Mycoplasma pneumoniae,
pubmed-meshheading:3146809-Pneumonia, Mycoplasma,
pubmed-meshheading:3146809-Retrospective Studies,
pubmed-meshheading:3146809-Tetracycline,
pubmed-meshheading:3146809-Time Factors
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pubmed:year |
1988
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pubmed:articleTitle |
Detection of specific IgM antibodies for the diagnosis of Mycoplasma pneumoniae infections: a clinical evaluation.
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pubmed:affiliation |
Department of Infectious Diseases, Orebro Medical Center Hospital, Sweden.
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pubmed:publicationType |
Journal Article
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