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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
5
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pubmed:dateCreated |
1989-3-14
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|
pubmed:abstractText |
Five HIV p24 antigen (p24Ag)-positive patients received alpha interferon during trials of therapy for hepatitis B. Four of these showed marked falls in p24Ag during treatment. One of the two patients who became p24Ag-negative [corrected] developed anti-p24 antibodies (anti-p24). Five out of nine p24Ag-negative HIV-antibody-positive patients showed a rise in anti-p24 titres during interferon therapy, whereas only two out of six untreated controls showed a similar rise. This study provides evidence that alpha interferon has anti-HIV activity in vivo.
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pubmed:grant |
|
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0269-9370
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
2
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
391-3
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|
pubmed:dateRevised |
2009-9-29
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|
pubmed:meshHeading |
pubmed-meshheading:3146270-Adult,
pubmed-meshheading:3146270-Clinical Trials as Topic,
pubmed-meshheading:3146270-HIV Antibodies,
pubmed-meshheading:3146270-HIV Antigens,
pubmed-meshheading:3146270-HIV Core Protein p24,
pubmed-meshheading:3146270-HIV Seropositivity,
pubmed-meshheading:3146270-Hepatitis B,
pubmed-meshheading:3146270-Humans,
pubmed-meshheading:3146270-Interferon Type I,
pubmed-meshheading:3146270-Middle Aged,
pubmed-meshheading:3146270-Random Allocation,
pubmed-meshheading:3146270-Retroviridae Proteins
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|
pubmed:year |
1988
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|
pubmed:articleTitle |
Suppression of HIV p24 antigen and induction of HIV anti-p24 antibody by alpha interferon in patients with chronic hepatitis B.
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|
pubmed:affiliation |
Department of Infectious Diseases, Royal Free Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
