Linked Life Data

3145902

Source:http://linkedlifedata.com/resource/pubmed/id/3145902

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12A
pubmed:dateCreated
1989-3-6
pubmed:abstractText
We report the cloning and molecular characterization of the swallow gene, a maternal-effect gene of Drosophila melanogaster. Maternal-effect genes are transcribed only during oogenesis; one such gene, bicoid, encodes a message that is localized at the anterior end of oocytes, eggs, and early embryos. swallow+ activity is necessary during oogenesis for bicoid message localization. We show here that a fragment of a previously identified clone, introduced into the genome by P-element-mediated transformation, is able to rescue the maternal-effect lethality of swallow mutants, confirming the identity of this clone as swallow. By in situ hybridization, we show that swallow message is synthesized in nurse cells during oogenesis but is not localized along either the anterior-posterior or dorsal-ventral axes. We have confirmed an earlier finding that the localization of bicoid message is defective in swallow- oocytes and eggs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0890-9369
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1655-65
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Molecular analysis of the swallow gene of Drosophila melanogaster.
pubmed:affiliation
Department of Biology, University of Rochester, New York 14627.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.