Linked Life Data

3144999

Source:http://linkedlifedata.com/resource/pubmed/id/3144999

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1989-2-17
pubmed:abstractText
Carbon dioxide measurements are not accurate, especially in children, if the response time of the carbon dioxide analyser is too slow and its output fails to reach the actual carbon dioxide concentration at the end of the breath. The distortion of the carbon dioxide waveform is a function of the "rise time" of the analyser. We have simulated an expired carbon dioxide curve and calculated the rise time required to measure accurately end-tidal carbon dioxide and VCO2 in adults and children. A rise time of 80 ms (10-70%) is sufficient to measure end-tidal carbon dioxide concentration with 5% accuracy in patients with rates of ventilation less than 100 b.p.m. and I:E ratios less than 2:1. We have measured the rise time of 11 commercially available carbon dioxide analysers and found that only six of the 11 responded quickly enough to be accurate for rates up to 100 b.p.m. All 11 responded rapidly enough to measure end-tidal carbon dioxide concentration with 5% accuracy when ventilatory rates were less than 30 b.p.m. To measure VCO2 with 5% accuracy, an analyser should have a rise time of 20 ms. Only one analyser met this specification. An analyser's rise time can be estimated clinically to within 10 (SD 8) ms by a simple breath hold and forced exhalation, thus providing an estimate of the accuracy of carbon dioxide measurements in adults or children.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
628-38
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
How the rise time of carbon dioxide analysers influences the accuracy of carbon dioxide measurements.
pubmed:affiliation
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City 84132.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't