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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1989-2-9
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pubmed:abstractText |
The rate of bactericidal activity of fleroxacin was compared with that of the combination of amoxycillin and clavulanic acid (in the proportion of 4 to 1) on beta-lactamase producing strains of Branhamella catarrhalis. The rate of bactericidal activity of 1 mg/l was as rapid as that of 1 mg/l of amoxycillin-clavulanic acid combination. This rate was not significantly more rapid if the concentrations of fleroxacin were increased to 10 mg/l. In conclusion, the bactericidal activity of fleroxacin is at least as good as that of the combination of amoxycillin and clavulanic acid. Fleroxacin showed a bactericidal effect for B. catarrhalis at concentrations that would be achieved in humans.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0305-7453
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22 Suppl D
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
43-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3144548-Amoxicillin,
pubmed-meshheading:3144548-Amoxicillin-Potassium Clavulanate Combination,
pubmed-meshheading:3144548-Anti-Infective Agents,
pubmed-meshheading:3144548-Ciprofloxacin,
pubmed-meshheading:3144548-Clavulanic Acids,
pubmed-meshheading:3144548-Culture Media,
pubmed-meshheading:3144548-Drug Therapy, Combination,
pubmed-meshheading:3144548-Fleroxacin,
pubmed-meshheading:3144548-Microbial Sensitivity Tests,
pubmed-meshheading:3144548-Moraxella (Branhamella) catarrhalis
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pubmed:year |
1988
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pubmed:articleTitle |
Rate of bactericidal activity for Branhamella catarrhalis of fleroxacin compared with that of amoxycillin-clavulanic acid.
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pubmed:affiliation |
Department of Microbiology, Brugmann University Hospital, Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study
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