Linked Life Data

3144038

Source:http://linkedlifedata.com/resource/pubmed/id/3144038

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1989-1-26
pubmed:abstractText
Using a coculture system, we have studied the local action of Sertoli cells on Leydig cell function. The results show that (i) both LH and FSH have equal potency to stimulate testosterone biosynthesis by fetal and neonatal testicular cells in an age-dependent manner, the maximum stimulation is observed between D3 and D5. (ii) An FSH-dependent factor(s) secreted by Sertoli cells increases the basal and/or LH-stimulated Leydig cell androgen production. (iii) The Sertoli cell-stimulating factor(s) is not a steroid or other small molecule, but a heat-labile peptide.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0253-5823
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
818-27
pubmed:dateRevised
2009-5-29
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
A factor(s) produced by Sertoli cells stimulates androgen biosynthesis by Leydig cells in neonatal rats.
pubmed:affiliation
Laboratory of Reproductive Biology, Institute of Zoology, Academia Sinica, Beijing.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't