Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1989-1-26
pubmed:abstractText
To define the role of bowel rest as an independent variable from nutritional support a prospective, randomised controlled trial was undertaken in 51 patients with active Crohn's disease unresponsive to other medical management. Nutritional support for 21 days was randomised to total parenteral nutrition and nil by mouth (n = 17), defined formula diet administered through a nasogastric tube (n = 19), or partial parenteral nutrition and oral food (n = 15). Nutrient input in the first two groups provided 40 non-protein kcal/kg ideal body weight /d and 1g/ kg/d protein respectively, while the third group received 15 non-protein kcal/kg/d and 0.3 g/kg/d protein intravenously and ate unrestricted food. Clinical remissions occurred in 71% of patients on parenteral nutrition, in 58% on the defined formula diet and in 60% on partial parenteral nutrition; the probability for each group of being in remission at one year, after successful therapy was 42%, 55%, and 56% respectively. These differences were not significant. In patients with active Crohn's disease bowel rest was not a major factor in achieving a remission during nutritional support and did not influence outcome during one year's follow-up.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-119060, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-16829411, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-3084344, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-3098648, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-3902590, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-3925172, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-414029, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-4212060, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-4214461, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6132218, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6148450, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6402050, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6428577, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6766373, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6773251, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6777233, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-6785134, http://linkedlifedata.com/resource/pubmed/commentcorrection/3143625-814826
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0017-5749
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1309-15
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Controlled trial of bowel rest and nutritional support in the management of Crohn's disease.
pubmed:affiliation
Department of Medicine, University of Toronto, Canada.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial