|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0010453,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0031586,
umls-concept:C0205225,
umls-concept:C0205355,
umls-concept:C0242275,
umls-concept:C1167622,
umls-concept:C1179149
|
|
pubmed:issue |
2-3
|
|
pubmed:dateCreated |
1979-11-21
|
|
pubmed:abstractText |
High affinity binding of epidermal growth factor (EGF) was detected with mouse epidermal cells in primary culture and with 2 epidermal cell lines maintained in permanent culture. EGF binding was inhibited by low concentrations of the tumor promoters 12-O-tetradecanoyl phorbol-13-acetate (TPA) and phorbol didecanoate (PDD), but not by the non-promoting phorbol esters 4-O-methyl TPA and 4 alpha-PDD.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0304-3835
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
71-7
|
|
pubmed:dateRevised |
2003-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:314329-Animals,
pubmed-meshheading:314329-Binding Sites,
pubmed-meshheading:314329-Cells, Cultured,
pubmed-meshheading:314329-Epidermal Growth Factor,
pubmed-meshheading:314329-Mice,
pubmed-meshheading:314329-Neoplasms, Experimental,
pubmed-meshheading:314329-Peptides,
pubmed-meshheading:314329-Phorbol Esters,
pubmed-meshheading:314329-Phorbols,
pubmed-meshheading:314329-Skin,
pubmed-meshheading:314329-Skin Neoplasms,
pubmed-meshheading:314329-Tetradecanoylphorbol Acetate
|
|
pubmed:year |
1979
|
|
pubmed:articleTitle |
Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters.
|
|
pubmed:publicationType |
Journal Article
|
