Linked Life Data

3142379

Source:http://linkedlifedata.com/resource/pubmed/id/3142379

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-11-28
pubmed:abstractText
Secretion of plasminogen activators (PA) by seminiferous tubules of hypophysectomized and hypophysectomized gonadotropin-treated rats was studied. Adult male hypophysectomized rats were treated with daily subcutaneous injections of saline, FSH (5 i.u.), hCG (100 i.u.), or FSH + hCG. At six and 10 days posthypophysectomy, segments of seminiferous tubules at stages VII-VIII of the epithelial cycle were isolated for culture in a serum-free medium. PA activity was determined by an indirect solid-phase radiometric assay from conditioned media. PA secretion was significantly decreased in seminiferous tubules from rats treated with saline, FSH, or hCG, whereas normal PA secretion was found in seminiferous tubules of FSH + hCG-treated rats. It is concluded that both FSH and LH, via stimulation of androgen secretion, are needed for the maintenance of normal PA secretion by rat seminiferous tubules.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0148-5016
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-27
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Plasminogen activator secretion in the rat seminiferous epithelium after hypophysectomy and gonadotropin treatment.
pubmed:affiliation
Livingston Reproductive Biology Laboratory, Department of Obstetrics and Gynecology, USC School of Medicine 90033.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't