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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1988-11-25
|
| pubmed:abstractText |
To gain better understanding of the natural history of Schistosoma haematobium associated disease, age- and intensity-related urinary tract morbidity were assessed in a cross-sectional study of Kilole (population 719) in Coast Province, Kenya. Overall prevalence of infection was 65% (39% light, 16% moderate, 9% heavy). Infection prevalence and mean intensity of infection were highest in the 5-14-year-old bracket for both sexes. Although significant intensity-associated increases in hematuria prevalence were noted for both children and adults in all infection categories, hematuria was more common in those less than 15 years of age. Children had a significant increase in the prevalence of dysuria at higher levels of infection, whereas adults did not. Radiographic study of a 1:9 random sample, stratified for age, revealed a greater prevalence of urinary tract granulomas in those less than 15 years. Subjects greater than 15 years of age had a greater frequency of hydronephrosis. Hydronephrosis, hydroureter, and bladder calcification were not associated with higher infection intensity. Among individuals with bladder calcification, a potential marker of cumulative inflammation, 87% had hydronephrosis or hydroureter, compared to a 40% prevalence among individuals without bladder calcification. These findings suggest that certain structural forms of urinary tract disease, such as hydronephrosis, progress during the course of untreated schistosomiasis haematobia despite age-related reductions in egg burden, whereas other forms of morbidity, such as hematuria, remain sensitive to the level of urinary egg excretion at the time of diagnosis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0002-9637
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
39
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
361-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3142286-Adolescent,
pubmed-meshheading:3142286-Adult,
pubmed-meshheading:3142286-Age Factors,
pubmed-meshheading:3142286-Analysis of Variance,
pubmed-meshheading:3142286-Animals,
pubmed-meshheading:3142286-Child,
pubmed-meshheading:3142286-Child, Preschool,
pubmed-meshheading:3142286-Female,
pubmed-meshheading:3142286-Humans,
pubmed-meshheading:3142286-Infant,
pubmed-meshheading:3142286-Kenya,
pubmed-meshheading:3142286-Male,
pubmed-meshheading:3142286-Middle Aged,
pubmed-meshheading:3142286-Schistosoma haematobium,
pubmed-meshheading:3142286-Schistosomiasis haematobia,
pubmed-meshheading:3142286-Sex Factors,
pubmed-meshheading:3142286-Ureter,
pubmed-meshheading:3142286-Urinary Bladder,
pubmed-meshheading:3142286-Urinary Tract,
pubmed-meshheading:3142286-Urography
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Urinary tract morbidity in schistosomiasis haematobia: associations with age and intensity of infection in an endemic area of Coast Province, Kenya.
|
| pubmed:affiliation |
Department of Medicine, Case Western Reserve University, Cleveland, Ohio.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|