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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-10-25
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pubmed:abstractText |
This paper is a retrospective review of 30 patients with esthesioneuroblastoma, an uncommon malignancy of the upper nasal cavity, treated at a single institution from 1959 through 1986. Over the period of study, there has been a gradual evolution of treatment policy and technique with the introduction of craniofacial resections and complex field megavoltage radiation, as well as for Stage C disease, the addition of chemotherapy to radiotherapy and surgery. The 25 patients with a 2 year minimum follow-up are divided into 2 groups depending upon treatment era to determine the impact of modern aggressive therapy upon treatment results. Two-year survival for Group I (1959-1975) was 70% as compared with 87% for Group II (1976-85). For Stage C disease, there was a definite improvement in survival in the later era (88% versus 50%), although relapses did not appear to be circumvented. Salvage therapy has an important role in prolonging survival in this disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
581-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3138210-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:3138210-Combined Modality Therapy,
pubmed-meshheading:3138210-Female,
pubmed-meshheading:3138210-Humans,
pubmed-meshheading:3138210-Male,
pubmed-meshheading:3138210-Middle Aged,
pubmed-meshheading:3138210-Neoplasm Recurrence, Local,
pubmed-meshheading:3138210-Neuroectodermal Tumors, Primitive, Peripheral,
pubmed-meshheading:3138210-Nose Neoplasms,
pubmed-meshheading:3138210-Radiotherapy, High-Energy,
pubmed-meshheading:3138210-Retrospective Studies
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pubmed:year |
1988
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pubmed:articleTitle |
Esthesioneuroblastoma: a comparison of two treatment eras.
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pubmed:affiliation |
Division of Therapeutic Radiology & Oncology, University of Virginia Medical Center, Charlottesville 22908.
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pubmed:publicationType |
Journal Article,
Comparative Study
|