Linked Life Data

3137231

Source:http://linkedlifedata.com/resource/pubmed/id/3137231

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-10-11
pubmed:abstractText
Eleven renal clear cell carcinomas were investigated with regard to their glycogen and glucose 6-phosphate (G6P) content and the activities of glycogen synthase and phosphorylase. Compared to normal cortex from the same kidneys, all tumours revealed increased glycogen and G6P content. The activities of phosphorylase a and b as well as of synthase R and D were also increased. Synthase I activity, however, was reduced. It was concluded that in these tumours glycogen synthesis may preferentially be catalyzed by synthase R which is activated by G6P. These findings agree with those in some other glycogenotic tissues and support the concept that an accumulation of G6P is associated with excessive storage of glycogen in preneoplastic and neoplastic lesions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0171-5216
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
369-72
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Activity of glycogen synthase and phosphorylase and glucose 6-phosphate content in renal clear cell carcinomas.
pubmed:affiliation
Institut für Experimentelle Pathologie, Deutsches Krebsforschungszentrum, Heidelberg, Federal Republic of Germany.
pubmed:publicationType
Journal Article