Linked Life Data

3136918

Source:http://linkedlifedata.com/resource/pubmed/id/3136918

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
1988-10-11
pubmed:abstractText
Subtractive hybridization was used to investigate differences in gene expression between a metastatic clone and nonmetastatic clone of the rat mammary adenocarcinoma line DMBA-8 which differ 100-fold in their metastatic behavior. Several differentially expressed highly homologous mRNAs (600 to 900 base pairs) were identified from the nonmetastatic line which are expressed at a level 20-fold higher than in the metastatic clone. Available sequence data show no homology to published gene sequences. There is no difference between the metastatic and nonmetastatic clones regarding DNA restriction fragment sizes or copy number of the gene. Expression of this newly described gene, named WDNM1, may be an important correlate of nonmetastasis in this tumor model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5203-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Differential expression of a novel gene, WDNM1, in nonmetastatic rat mammary adenocarcinoma cells.
pubmed:affiliation
Department of Medicine, University of Sydney, Westmead, New South Wales, Australia.
pubmed:publicationType
Journal Article