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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1988-9-16
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pubmed:abstractText |
Employing high-performance liquid chromatography with isocratic elution using a two-column system (mu Bondapak C18 and mu Bondapak CN) and phenyl isothiocyanate as a fluorogenic reagent, NG-monomethylarginine (MMA). NG-dimethylarginines, and epsilon-N-trimethyllysine (TML) can be quatitatively separated from human serum samples. The recoveries of these amino acids were over 90%. It was observed that the serum concentrations of MMA, DMA and TML were significantly elevated in sera obtained from patients suffering from diabetes mellitus, hepatitis or hyperthyroidism, particularly the last condition.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-9673
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
440
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-30
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3136187-Amino Acids,
pubmed-meshheading:3136187-Chromatography, High Pressure Liquid,
pubmed-meshheading:3136187-Humans,
pubmed-meshheading:3136187-Hyperthyroidism,
pubmed-meshheading:3136187-Lysine,
pubmed-meshheading:3136187-Methylation,
pubmed-meshheading:3136187-o-Phthalaldehyde
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pubmed:year |
1988
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pubmed:articleTitle |
Determination of methylated amino acids in human serum by high-performance liquid chromatography.
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pubmed:affiliation |
Fels Research Institute, Temple University School of Medicine, Philadelphia, PA 19140.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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