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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1988-9-12
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pubmed:abstractText |
The hst-1 gene, previously designated as the hst gene, and seven other oncogenes were examined for possible structural changes in esophageal, gastric and colorectal carcinomas by Southern blot hybridization. The hst-1 gene was amplified in eight (42.1%) of the nineteen esophageal squamous cell carcinomas and in all four metastatic tumors of lymph nodes. The degree of amplification ranged from two to eight times. Coamplification of the hst-1 and c-erbB-1 gene was found in one case of esophageal carcinoma. However, no amplification of the hst-1 gene was detected in gastric and colorectal carcinomas.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0910-5050
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
584-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3136110-Adult,
pubmed-meshheading:3136110-Aged,
pubmed-meshheading:3136110-Esophageal Neoplasms,
pubmed-meshheading:3136110-Female,
pubmed-meshheading:3136110-Gene Amplification,
pubmed-meshheading:3136110-Humans,
pubmed-meshheading:3136110-Male,
pubmed-meshheading:3136110-Middle Aged,
pubmed-meshheading:3136110-Oncogenes
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pubmed:year |
1988
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pubmed:articleTitle |
Amplification of the hst-1 gene in human esophageal carcinomas.
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pubmed:affiliation |
Department of Pathology, Hiroshima University School of Medicine.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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