Linked Life Data

3135493

Source:http://linkedlifedata.com/resource/pubmed/id/3135493

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-8-30
pubmed:abstractText
One acid alpha-glucosidase and two neutral alpha-glucosidases were separated from human skeletal muscle by DEAE-cellulose column chromatography. The appearance of the two human neutral alpha-glucosidase isoenzymes was found to be age dependent. We called them "fetal" and "adult" neutral alpha-glucosidases. The biochemical properties of the fetal and adult types of neutral alpha-glucosidases appeared to be similar to those previously reported for neutral alpha-glucosidases AB and C, respectively. The neutral alpha-glucosidase activity in the column eluate of the infantile acid maltase deficiency (AMD; 5-month-old) muscle was completely of the adult type, whereas 18% of the total neutral alpha-glucosidase activity in age-matched control muscle was of the fetal type. In contrast, the eluate of the late-onset AMD (32-year-old) muscle contained both the adult and fetal neutral alpha-glucosidases, 68 and 32%, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0148-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-71
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
alpha-Glucosidase isoenzymes in normal and acid maltase-deficient human skeletal muscles.
pubmed:affiliation
National Institute of Neuroscience, NCNP, Tokyo, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't