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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1988-9-8
|
| pubmed:abstractText |
The adult male accessory glands of D. melanogaster synthesize and secrete a peptide that represses female sexual receptivity and stimulates oviposition. Normally, this peptide is transferred to females during copulation; however, the peptide shows the same biological activity after purification and subsequent injection into the abdominal cavity of female virgins. Amino acid sequencing of the purified peptide and oligonucleotide-directed cDNA cloning established that the peptide consists of 36 amino acids. It appears to be synthesized as a precursor with a hydrophobic signal sequence of 19 residues at its N-terminal end. The precursor peptide is encoded by a short mRNA that accumulates exclusively in the male accessory gland. The gene has been localized by in situ hybridization to polytene chromosomes at 70A.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0092-8674
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
29
|
| pubmed:volume |
54
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
291-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3135120-Amino Acid Sequence,
pubmed-meshheading:3135120-Animals,
pubmed-meshheading:3135120-Chromatography, High Pressure Liquid,
pubmed-meshheading:3135120-Cloning, Molecular,
pubmed-meshheading:3135120-DNA,
pubmed-meshheading:3135120-Drosophila Proteins,
pubmed-meshheading:3135120-Drosophila melanogaster,
pubmed-meshheading:3135120-Female,
pubmed-meshheading:3135120-Gene Expression Regulation,
pubmed-meshheading:3135120-Male,
pubmed-meshheading:3135120-Molecular Sequence Data,
pubmed-meshheading:3135120-Nucleic Acid Hybridization,
pubmed-meshheading:3135120-Oviposition,
pubmed-meshheading:3135120-Ovulation,
pubmed-meshheading:3135120-Peptide Biosynthesis,
pubmed-meshheading:3135120-Peptides,
pubmed-meshheading:3135120-RNA, Messenger,
pubmed-meshheading:3135120-Sexual Behavior, Animal
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
A male accessory gland peptide that regulates reproductive behavior of female D. melanogaster.
|
| pubmed:affiliation |
Institute of Zoology, University of Zürich, Switzerland.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|