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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1988-8-11
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pubmed:abstractText |
Since November 1983, a multidisciplinary protocol for the treatment of pancreatic carcinoma has been used for eight patients at the National Cancer Center Hospital. This therapy includes an extended pancreatic resection, intra-operative irradiation with 3,000 rad of electrons using a microton, and an intra-operative hepatic arterial or portal infusion of mitomycin C, 10 mg. Furthermore, post-operative chemotherapy with mitomycin C (10 mg to 10 mg x 3) is added by Seldinger's method or intravenously (i.v.). The post-operative course was uneventful in all eight patients. Although the number of patients treated is small, the one-year survival rate was 86%. This rate is markedly better than the 28% after conventional radical pancreatectomy from 1962 to 1983. According to our experience, pancreatic carcinoma is unlikely to be cured by only radical operative procedures. A multidisciplinary treatment protocol as an adjunct to radical surgery appears necessary for a good prognosis of this disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0169-4197
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
249-59
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3133433-Aged,
pubmed-meshheading:3133433-Combined Modality Therapy,
pubmed-meshheading:3133433-Humans,
pubmed-meshheading:3133433-Infusions, Intra-Arterial,
pubmed-meshheading:3133433-Intraoperative Care,
pubmed-meshheading:3133433-Middle Aged,
pubmed-meshheading:3133433-Mitomycin,
pubmed-meshheading:3133433-Mitomycins,
pubmed-meshheading:3133433-Pancreatic Neoplasms
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pubmed:year |
1988
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pubmed:articleTitle |
Multidisciplinary treatment for resectable pancreatic cancer.
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pubmed:affiliation |
Department of Surgery, National Cancer Center Hospital, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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