Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1988-7-25
|
pubmed:abstractText |
Peripheral blood leucocytes from patients who had recently had measles infection were examined for their ability to produce alpha- or gamma-interferon, their antiviral state and the level of E enzyme. These results were compared with peripheral blood leucocytes from healthy control subjects. The results show that while peripheral blood leucocytes from control patients produced alpha- and gamma-interferon, those from the measles patients produced only alpha-interferon. The peripheral blood leucocytes from all the measles patients were in an antiviral state whereas those from only 20% of the controls were in this state. Since gamma-interferon is mainly produced by T lymphocytes, the lack of gamma-interferon production by peripheral blood leucocytes from patients with measles correlates with previously reported depressed T-cell function in patients after measles infection.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0256-9574
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
18
|
pubmed:volume |
73
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
711-2
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:3132743-Adolescent,
pubmed-meshheading:3132743-Child,
pubmed-meshheading:3132743-Child, Preschool,
pubmed-meshheading:3132743-Female,
pubmed-meshheading:3132743-Humans,
pubmed-meshheading:3132743-Infant,
pubmed-meshheading:3132743-Interferon Type I,
pubmed-meshheading:3132743-Interferon-gamma,
pubmed-meshheading:3132743-Leukocytes,
pubmed-meshheading:3132743-Male,
pubmed-meshheading:3132743-Measles
|
pubmed:year |
1988
|
pubmed:articleTitle |
Interferon status after measles virus infection.
|
pubmed:affiliation |
Department of Virology, University of the Witwatersrand and National Institute for Virology, Johannesburg.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|