rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1988-7-25
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pubmed:databankReference |
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pubmed:abstractText |
We have isolated a cDNA copy of a truncated C gamma 2b transcript produced by Abelson murine leukemia virus transformants that spontaneously switch from mu to gamma 2b. The initiation site of this transcript was 2 kilobases 5' to the gamma 2b switch recombination region, demonstrating its germ line origin. Nucleotide sequence analyses suggest that this transcript does not encode a protein. Expression of germ line gamma 2b transcripts in Abelson murine leukemia virus transformants and in normal spleen cells correlated with endogenous gamma 2b class switch activity.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-117549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3007121,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3028778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3034595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3038529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3081434,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3106486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3112560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3917574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-3934561,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-6259538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-6804095,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-6810096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3132612-6817925
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0270-7306
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1849-52
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3132612-Abelson murine leukemia virus,
pubmed-meshheading:3132612-Animals,
pubmed-meshheading:3132612-B-Lymphocytes,
pubmed-meshheading:3132612-Base Sequence,
pubmed-meshheading:3132612-Cell Line, Transformed,
pubmed-meshheading:3132612-Genes, Immunoglobulin,
pubmed-meshheading:3132612-Immunoglobulin Heavy Chains,
pubmed-meshheading:3132612-Immunoglobulin gamma-Chains,
pubmed-meshheading:3132612-Immunoglobulin mu-Chains,
pubmed-meshheading:3132612-Molecular Sequence Data,
pubmed-meshheading:3132612-Transcription, Genetic
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pubmed:year |
1988
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pubmed:articleTitle |
Structure and expression of germ line immunoglobulin gamma 2b transcripts.
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pubmed:affiliation |
Howard Hughes Medical Institute, New York, New York.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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