Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1988-5-31
|
| pubmed:abstractText |
In ten eucapnic patients with chronic obstructive lung disease (COLD) we evaluated the breathing pattern during induced progressive hypercapnia (CO2 rebreathing) and progressive exercise on an ergometric bicycle (30 W/3 min). The time and volume components of the respiratory cycle were measured breath by breath. When compared to hypercapnia, the increase in ventilation (VE) during exercise was associated with a smaller increase in tidal volume (VT) and a greater increase in respiratory frequency (fR). Plots of tidal volume (VT) against both inspiratory time (TI) and expiratory time (TE) showed a greater decrease in both TI and TE during exercise than with hypercapnia. Analysis of VE in terms of flow (VT/TI) and timing (TI/TT) showed VE to increase by a similar increase to that in VT/TI during both exercise and hypercapnia, while TI/TT did not change significantly. When the patients were matched for a given VE (28 l.min-1), exercise induced a smaller increase in VT (p less than 0.05), a greater increase in fR (p less than 0.025); TI (p less than 0.025) and TE (p less than 0.01) were found to be smaller during exercise than hypercapnia. The change in the off-switch mechanism during exercise and hypercapnia could account for our results.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0903-1936
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
139-44
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:3129301-Adult,
pubmed-meshheading:3129301-Aged,
pubmed-meshheading:3129301-Carbon Dioxide,
pubmed-meshheading:3129301-Humans,
pubmed-meshheading:3129301-Hypercapnia,
pubmed-meshheading:3129301-Lung Diseases, Obstructive,
pubmed-meshheading:3129301-Male,
pubmed-meshheading:3129301-Middle Aged,
pubmed-meshheading:3129301-Physical Exertion,
pubmed-meshheading:3129301-Pulmonary Ventilation,
pubmed-meshheading:3129301-Respiration,
pubmed-meshheading:3129301-Tidal Volume
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Influence of exercise and CO2 on breathing pattern in patients with chronic obstructive lung disease (COLD).
|
| pubmed:affiliation |
Clinica Medica III, Università di Firenze, Italy.
|
| pubmed:publicationType |
Journal Article
|