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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-4-28
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pubmed:abstractText |
Eighty-five patients with chronic splenomegaly and proven oesophageal varices were studied at Kenyatta National Hospital, Nairobi. The major defined groups were hepatosplenic schistosomiasis (24%), cirrhosis (20%) and portal vein occlusion (11%). Hyper-reactive malarial splenomegaly (tropical splenomegaly syndrome) was considered as the cause of oesophageal varices in only one patient. In 26% of cases liver biopsy was non-diagnostic and the extrahepatic portal vein was demonstrated radiologically to be patent. Such patients were thought to be suffering from idiopathic portal hypertension, not previously described elsewhere in Africa. Hepatitis B surface antigen was detected in 12% of controls and in 58% of patients with cirrhosis (p less than 0.001). Some serological marker of previous hepatitis B virus infection was present in 92% of patients with cirrhosis and in 79% of controls. Kamba patients from Machakos and Kitui Districts were significantly more prevalent than expected among these 85 cases of portal hypertension.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0035-9203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3127951-Esophageal and Gastric Varices,
pubmed-meshheading:3127951-Hepatitis B Core Antigens,
pubmed-meshheading:3127951-Hepatitis B Surface Antigens,
pubmed-meshheading:3127951-Humans,
pubmed-meshheading:3127951-Hypertension, Portal,
pubmed-meshheading:3127951-Kenya,
pubmed-meshheading:3127951-Liver Cirrhosis,
pubmed-meshheading:3127951-Schistosomiasis mansoni,
pubmed-meshheading:3127951-Splenomegaly
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pubmed:year |
1987
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pubmed:articleTitle |
Chronic splenomegaly in Nairobi, Kenya. II. Portal hypertension.
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pubmed:affiliation |
Dept. of Medicine, Kenyatta National Hospital, Nairobi, Kenya.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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