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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1988-3-2
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pubmed:abstractText |
Three patients who received antithymocyte globulin therapy for severe aplastic anemia due to gold therapy are described. In 2 patients the hemoglobin, white blood cell count and neutrophils were normal and platelet counts exceeded 100 X 10(9)/1 more than 2 years after treatment. The 3rd patient did not respond to antithymocyte globulin or to cyclosporine therapy; subsequent allogeneic bone marrow transplantation resulted in satisfactory engraftment at 12 months. In all 3 patients the arthritis was improved after the episode of marrow aplasia and its treatment. Including these 3 patients, 12 reported patients with severe aplastic anemia due to gold have now been treated with antithymocyte globulin; 8 have shown significant improvement. These results are better than those reported for any other treatment. Antithymocyte globulin may be optimal initial treatment for this serious disorder.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0315-162X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
14
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
1026-9
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3123673-Adult,
pubmed-meshheading:3123673-Aged,
pubmed-meshheading:3123673-Anemia, Aplastic,
pubmed-meshheading:3123673-Antilymphocyte Serum,
pubmed-meshheading:3123673-Arthritis, Rheumatoid,
pubmed-meshheading:3123673-Bone Marrow Transplantation,
pubmed-meshheading:3123673-Combined Modality Therapy,
pubmed-meshheading:3123673-Cyclosporins,
pubmed-meshheading:3123673-Female,
pubmed-meshheading:3123673-Gold Sodium Thiomalate,
pubmed-meshheading:3123673-Humans,
pubmed-meshheading:3123673-Male,
pubmed-meshheading:3123673-Middle Aged
|
pubmed:year |
1987
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pubmed:articleTitle |
Immunosuppression as initial treatment for gold induced aplastic anemia.
|
pubmed:affiliation |
Department of Medicine, University of Alberta Hospital, Edmonton, Canada.
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pubmed:publicationType |
Journal Article,
Case Reports
|