Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-3-24
pubmed:abstractText
Cutaneous levels of soluble interleukin-2 receptor (Tac peptide) have been measured in tuberculin responses in 13 human volunteers by assaying the fluid present in suction-induced blisters at various times after injection of standard purified protein derivative of tuberculin (PPD). Low levels of Tac peptide were found in blisters without prior injection of PPD and in PPD-negative individuals, and maximal levels of Tac peptide were correlated with increased induration at 48 hr (r = 0.69, P = 0.04) in PPD-positive subjects. This is the first report of measurement of Tac peptide in vivo in a defined immune response in man, and may offer a new approach to the study of human immune function in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0090-1229
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
450-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Release of soluble interleukin-2 receptors (Tac peptide) in vivo during human immune responses to tuberculin.
pubmed:affiliation
Department of Pathology Leprosy Atelier, University of Hawaii, Honolulu 96816.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't