Linked Life Data

3122539

Source:http://linkedlifedata.com/resource/pubmed/id/3122539

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-2-5
pubmed:abstractText
The influence of ethanol treatment on various enzymes involved in the metabolism of polyamines, substances implicated in cell physiology, growth and differentiation, is reviewed. In particular, we studied the effect of acute in utero ethanol exposure on fetal liver diamine oxidase, the enzyme involved in the oxidative deamination of biogenic amines as well as in the terminal catabolism of polyamines. Ethanol, in contrast to that previously observed in adult rat liver, caused in fetal liver a significant diminution in diamine oxidase activity, which appeared reversible and was not dose-dependent with 2 or 4 g/kg body weight. These findings and the possible implication of altered polyamine metabolism in the pathogenesis of fetal alcohol syndrome are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0270-3106
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
73-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Ethanol and polyamine metabolism in adult and fetal tissues: possible implication in fetus damage.
pubmed:affiliation
Consiglio Nazionale delle Ricerche, Center for Research in Cell Pathology, Milan, Italy.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't