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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1987-12-21
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pubmed:abstractText |
Only partial studies evaluating the endocrine profile in molar pregnancy have been performed. In order to characterize the neuro-endocrine pattern during and after molar pregnancy, we studied the basal hormonal levels of hCG, human placental lactogen (hPL), FSH, GH, TSH, free thyroxine index (FTI), oestradiol-17 beta (E2), and progesterone (PG), as well as the anterior pituitary response to TRH, GnRH, and hypoglycaemia induced by insulin in 7 patients during molar pregnancy and one week after molar abortion. hCG showed significantly higher serum levels during rather than after molar pregnancy and hPL was detectable in only 4 patients during, but in none after molar pregnancy. FSH values were in the follicular phase range before and after molar abortion (12.7 +/- 0.8 and 12.7 +/- 3.5 IU/l). PRL had elevated basal levels before and after molar abortion; 103.0 +/- 16.5 and 43 +/- 10.6 micrograms/l, respectively (P less than 0.05). GH levels were distinctly elevated in 3 patients during molar pregnancy; after molar abortion, the basal GH values were normal in all patients less than 10 micrograms/l. Basal cortisol and TSH levels were in the normal range before and after molar abortion. The FTI was above the normal range in 3 patients during molar pregnancy, whereas after molar abortion the values were normalized. E2 levels were elevated before and after molar abortion, 1881 +/- 477 and 96.5 +/- 39.2 ng/l, respectively (P less than 0.01). PG levels before and after molar abortion were 30.9 +/- 5.4 and 10 +/- 6.7 micrograms/l, respectively (P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chorionic Gonadotropin,
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Follicle Stimulating Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrocortisone,
http://linkedlifedata.com/resource/pubmed/chemical/Pituitary Hormone-Releasing Hormones,
http://linkedlifedata.com/resource/pubmed/chemical/Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Prolactin,
http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin-Releasing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Thyroxine
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0001-5598
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-80
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:3120449-Adolescent,
pubmed-meshheading:3120449-Adult,
pubmed-meshheading:3120449-Chorionic Gonadotropin,
pubmed-meshheading:3120449-Estradiol,
pubmed-meshheading:3120449-Female,
pubmed-meshheading:3120449-Follicle Stimulating Hormone,
pubmed-meshheading:3120449-Growth Hormone,
pubmed-meshheading:3120449-Humans,
pubmed-meshheading:3120449-Hydatidiform Mole,
pubmed-meshheading:3120449-Hydrocortisone,
pubmed-meshheading:3120449-Hypoglycemia,
pubmed-meshheading:3120449-Pituitary Gland, Anterior,
pubmed-meshheading:3120449-Pituitary Hormone-Releasing Hormones,
pubmed-meshheading:3120449-Pregnancy,
pubmed-meshheading:3120449-Progesterone,
pubmed-meshheading:3120449-Prolactin,
pubmed-meshheading:3120449-Thyrotropin-Releasing Hormone,
pubmed-meshheading:3120449-Thyroxine
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pubmed:year |
1987
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pubmed:articleTitle |
Neuroendocrine regulation of anterior pituitary function in patients during and after molar pregnancy.
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pubmed:affiliation |
Unidad de Investigacion Biomedica del Noreste, IMSS, Nuevo Leon, Mexico.
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pubmed:publicationType |
Journal Article
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