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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1988-1-14
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pubmed:abstractText |
Seventy-nine patients with endoscopically confirmed gastric ulcers received either ranitidine (37 patients) or misoprostol (42 patients) in a randomized double-blind manner. Fifty-six percent of the patients treated with ranitidine, and 38% of those treated with misoprostol presented with endoscopically healed ulcers after four weeks of treatment. After eight weeks complete healing had occurred in 86% of the patients receiving ranitidine, and 74% of those on misoprostol. These differences were not statistically significant. In smokers, ranitidine was superior to misoprostol, leading to a higher healing rate at four weeks (73% versus 20%). Thus there was no evidence that in patients with gastric ulcer misoprostol overcomes the negative effect of cigarette smoking.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0172-6390
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
34
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
233-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3119449-Adult,
pubmed-meshheading:3119449-Aged,
pubmed-meshheading:3119449-Alprostadil,
pubmed-meshheading:3119449-Clinical Trials as Topic,
pubmed-meshheading:3119449-Double-Blind Method,
pubmed-meshheading:3119449-Female,
pubmed-meshheading:3119449-Humans,
pubmed-meshheading:3119449-Male,
pubmed-meshheading:3119449-Middle Aged,
pubmed-meshheading:3119449-Misoprostol,
pubmed-meshheading:3119449-Random Allocation,
pubmed-meshheading:3119449-Ranitidine,
pubmed-meshheading:3119449-Smoking,
pubmed-meshheading:3119449-Stomach Ulcer
|
pubmed:year |
1987
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pubmed:articleTitle |
Gastric ulcer: a double blind comparison of 800 mcg misoprostol versus 300 mg ranitidine.
|
pubmed:affiliation |
Division of Gastroenterology CHUV-PMU, University of Lausanne.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|