Linked Life Data

3118592

Source:http://linkedlifedata.com/resource/pubmed/id/3118592

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1987-12-2
pubmed:abstractText
The aim of this study was to identify a streptococcal cell wall substance which is able to bind to epithelial cells. The water-soluble phase of sonicated M+ and M- strains was incubated with pharyngeal and buccal epithelial cells. Electrophoretic analysis of these materials, before and after incubation, showed disappearance of one band from the M+ samples only, after incubation with pharyngeal epithelial cells. The specific anti-M protein serum did not precipitate this protein. Incubation of tested materials with buccal epithelial cells did not change their composition. The molecular mass of this band was estimated as 35,000 Daltons by the use of SDS-PAGE and marker proteins. These results suggest that an adhesin responsible for the streptococcal group A binding to pharyngeal epithelial cells is a protein closely associated with the M antigen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0176-6724
pubmed:author
pubmed:issnType
Print
pubmed:volume
265
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
146-50
pubmed:dateRevised
2009-6-8
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Streptococcus pyogenes cell wall protein responsible for binding to pharyngeal epithelial cells.
pubmed:affiliation
Department of Bacteriology, National Institute of Hygiene, Warszawa, Poland.
pubmed:publicationType
Journal Article