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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1987-11-9
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pubmed:abstractText |
The aim of this study was to examine the effect in vitro of gold sodium thiomalate (GST) on interleukin 1 (IL-1), and interleukin 2 (IL-2) production and IL-2 receptor expression in thymocytes of mice and in human peripheral blood mononuclear cells (PBMC). GST increased the proliferation of thymocytes and PBMC to suboptimal doses of T cell mitogens Con A and PHA. It induced IL-1 production of the accessory adherent cells within thymocytes and PBMC, IL-1 production in the murine macrophage line P388D1 and induced the PHA reactive thymocytes to produce IL-2 and to express IL-2 receptors. The significance of these findings is discussed.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-134715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-2935633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-2981168,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-2981169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-307029,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-308989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-315070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-315430,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-3920312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-3922920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-403043,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-406862,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-414757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-4580005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-4580006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-4596067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-4861748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-4864541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6217341,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6229937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6426923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6427923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6606015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6608107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6692894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6770028,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6785748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6787168,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6804369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6806357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6965769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-6968268,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-7042543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-811742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-826117,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3115645-838859
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-9104
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-65
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3115645-Animals,
pubmed-meshheading:3115645-Female,
pubmed-meshheading:3115645-Gold Sodium Thiomalate,
pubmed-meshheading:3115645-Humans,
pubmed-meshheading:3115645-Interleukin-1,
pubmed-meshheading:3115645-Interleukin-2,
pubmed-meshheading:3115645-Leukocytes,
pubmed-meshheading:3115645-Lymphocyte Activation,
pubmed-meshheading:3115645-Mice,
pubmed-meshheading:3115645-Mice, Inbred C3H,
pubmed-meshheading:3115645-Mitogens,
pubmed-meshheading:3115645-Receptors, Immunologic,
pubmed-meshheading:3115645-Receptors, Interleukin-2,
pubmed-meshheading:3115645-T-Lymphocytes
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pubmed:year |
1987
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pubmed:articleTitle |
In vitro effects of gold sodium thiomalate on IL-1, IL-2 production, IL-2 receptor expression and IL-2 responsiveness in thymocytes and peripheral blood mononuclear cells.
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pubmed:affiliation |
Free University of Berlin, Department of Dematology, Rudolf Virchow Clinic.
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pubmed:publicationType |
Journal Article
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