Linked Life Data

3115272

Source:http://linkedlifedata.com/resource/pubmed/id/3115272

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
1987-10-14
pubmed:abstractText
Acute phase responses of plasma angiotensinogen and kininogen were studied in rats. Plasma angiotensinogen levels increased about 3-fold during the first 8 hr, and returned to normal at 48 hr, following the induction of acute inflammation by lipopolysaccharide (LPS). Plasma kininogen reached maximum levels at 48 hr following LPS administration. In adrenalectomized rats, plasma angiotensinogen levels decreased significantly, and the administration of LPS did not elevate plasma angiotensinogen levels. In contrast, plasma kininogen levels were increased by adrenalectomy, as well as by sham-operation. Dexamethasone significantly increased plasma angiotensinogen levels in adrenalectomized rats as well as in normal rats, but aldosterone did not. Plasma kininogen levels of normal rats were not changed by the administration of dexamethasone or aldosterone. From these results, it was concluded that the acute phase response of plasma angiotensinogen is mediated by glucocorticoid, but that of plasma kininogen is not.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-2952
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3069-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Acute phase responses of plasma angiotensinogen and T-kininogen in rats.
pubmed:publicationType
Journal Article, Comparative Study