Linked Life Data

3115246

Source:http://linkedlifedata.com/resource/pubmed/id/3115246

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
81
pubmed:dateCreated
1987-10-21
pubmed:abstractText
Monoclonal antibodies capable of exerting agonistic functions toward surface receptors of human T lymphocytes are employed to study discrete signals involved in T cell activation via two differential pathways (antigen-induced and "alternative" pathway of T cell activation). The studies to be reported demonstrate that these two modes of T cell triggering are independent of each other since the respective cell surface molecules with which T cells interact in the initiation of activation and the requirements for monokines are clearly distinct. Moreover, preliminary investigations of various types of secondary immunodeficiencies suggest that immunologic dysfunction can be attributed to blockades at particular levels of the activation cascade.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0301-0457
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Two pathways of T cell activation.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't