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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3-4
|
| pubmed:dateCreated |
1987-10-6
|
| pubmed:abstractText |
Effects of vanillin on the induction of sister-chromatid exchanges (SCEs) and structural chromosome aberrations by mitomycin C (MMC) were investigated in cultured Chinese hamster ovary cells. Vanillin induced neither SCEs nor chromosome aberrations by itself. However, an obvious increase in the frequency of SCEs was observed when MMC-treated cells were cultured in the presence of vanillin. The effect of vanillin was S-phase-dependent. On the contrary, the frequency of cells with chromosome aberrations was significantly decreased by the post-treatment with vanillin at G2 phase.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0027-5107
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
191
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
193-200
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3114631-Animals,
pubmed-meshheading:3114631-Benzaldehydes,
pubmed-meshheading:3114631-Cell Cycle,
pubmed-meshheading:3114631-Cell Line,
pubmed-meshheading:3114631-Chromosome Aberrations,
pubmed-meshheading:3114631-Cricetinae,
pubmed-meshheading:3114631-Drug Administration Schedule,
pubmed-meshheading:3114631-Drug Synergism,
pubmed-meshheading:3114631-Mitomycin,
pubmed-meshheading:3114631-Mitomycins,
pubmed-meshheading:3114631-Sister Chromatid Exchange
|
| pubmed:articleTitle |
Effects of vanillin on sister-chromatid exchanges and chromosome aberrations induced by mitomycin C in cultured Chinese hamster ovary cells.
|
| pubmed:publicationType |
Journal Article
|