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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1987-9-21
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pubmed:abstractText |
The regulation of renin and renin messenger RNA (mRNA) in the rat ovary was examined to test the hypothesis that the expression of renin gene and the secretion of renin in the ovary is the estrogen-mediated process that responds to follicle-stimulating hormone (FSH). In the ovary of the immature 25-day female rats, the concentration of renin mRNA was comparatively low, but 36 h after injection of FSH, the renin mRNA content showed a three-fold increase compared to the basal level. This increase was consistent with the stimulation of the total renin concentration in the ovary. On the other hand, the total renin concentration in the rat uterus gradually decreased, suggesting that the enhancement of the contents of renin and renin mRNA by FSH is an ovary-specific phenomenon. In hypophysectomized rats, the total renin concentration in the rat ovary was stimulated by the estrogen as well as FSH. These findings suggest that the production of ovarian renin is regulated by the pituitary hormone, particularly FSH.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
|
pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
989-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3113439-Animals,
pubmed-meshheading:3113439-Estradiol,
pubmed-meshheading:3113439-Female,
pubmed-meshheading:3113439-Follicle Stimulating Hormone,
pubmed-meshheading:3113439-Gene Expression Regulation,
pubmed-meshheading:3113439-Genes,
pubmed-meshheading:3113439-Kinetics,
pubmed-meshheading:3113439-Ovary,
pubmed-meshheading:3113439-RNA, Messenger,
pubmed-meshheading:3113439-Rats,
pubmed-meshheading:3113439-Rats, Inbred Strains,
pubmed-meshheading:3113439-Renin,
pubmed-meshheading:3113439-Transcription, Genetic
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pubmed:year |
1987
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pubmed:articleTitle |
Ovarian renin gene expression is regulated by follicle-stimulating hormone.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|