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pubmed:abstractText |
F antigen is a liver protein of unknown function previously thought to be confined to class Mammalia. Using a recently developed radioimmunoassay, we show that F antigen can also be found in classes Aves, Reptilia, Amphibia and Osteichthyes. Ouchterlony gel diffusion (using murine antibodies) gave lines of identity or partial identity between mammalian F antigens, a line of identity between avian and reptilian F antigens (each showing partial identity to mammalian) and no precipitation with fish or amphibian F antigens. All immunopurified F antigens have molecular weights of 40,000-45,000.
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