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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1987-9-23
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pubmed:abstractText |
We describe an ELISA technique able to recognize malondialdehyde-modified low-density lipoproteins (LDL). For this purpose we produced antibodies to malondialdehyde-LDL, specific for the malondialdehyde modification of LDL; these antibodies recognized essentially malondialdehyde-LDL. Coating ELISA plates with the antibodies to malondialdehyde-LDL and using peroxidase-labelled antibodies to LDL, which reveal only apolipoprotein B, we obtained an accurate method of detecting malondialdehyde-modified apolipoprotein B. Preliminary studies demonstrated that this method allows the detection of lipoproteins containing malondialdehyde-modified apolipoprotein B in the serum of patients with cardiovascular diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
920
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
215-20
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3111542-Animals,
pubmed-meshheading:3111542-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3111542-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:3111542-Immunodiffusion,
pubmed-meshheading:3111542-Lipoproteins, LDL,
pubmed-meshheading:3111542-Malonates,
pubmed-meshheading:3111542-Malondialdehyde,
pubmed-meshheading:3111542-Monocytes,
pubmed-meshheading:3111542-Rabbits
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pubmed:year |
1987
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pubmed:articleTitle |
Immunological detection of low-density lipoproteins modified by malondialdehyde in vitro or in vivo.
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pubmed:publicationType |
Journal Article
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