| pubmed-article:3111001 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0025663 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0032143 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0184511 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0678257 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:3111001 | lifeskim:mentions | umls-concept:C0449851 | lld:lifeskim |
| pubmed-article:3111001 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3111001 | pubmed:dateCreated | 1987-8-7 | lld:pubmed |
| pubmed-article:3111001 | pubmed:abstractText | Three methods for measurement of tissue plasminogen activator (t-PA) activity in plasma were compared with regard to linearity, precision and clinical applicability. Based on this comparison a new improved technique is described. The 3 methods differed in the way the influence of inhibitors in plasma was eliminated. In method A t-PA was measured in acidified plasma, in method B in euglobulin precipitate and in method C after adsorption of plasma on lysine-Sepharose. After addition of 15 IU/ml of t-PA to normal plasma the recovery with method A was 17.4 +/- 2.4 IU/ml, with method B 11.4 +/- 0.5 IU/ml and with method C 9.8 +/- 0.9 IU/ml. When tested on venous stasis plasma from 10 patients the 3 methods correlated well with a correlation coefficient of r = 0.97 - 0.99. Significantly higher values were found in acidified plasma (method A) as compared to the other methods. From this evaluation a method for determination of t-PA activity using acidification and internal standard to abolish the influence of inhibitors and poly-D-lysine as a stimulator was selected. The recovery with this method was 103.4 +/- 8.5% independent of PA inhibitor content in the plasma. | lld:pubmed |
| pubmed-article:3111001 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3111001 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3111001 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3111001 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3111001 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3111001 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3111001 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3111001 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3111001 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3111001 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:3111001 | pubmed:issn | 0049-3848 | lld:pubmed |
| pubmed-article:3111001 | pubmed:author | pubmed-author:ErikssonEE | lld:pubmed |
| pubmed-article:3111001 | pubmed:author | pubmed-author:RisbergBB | lld:pubmed |
| pubmed-article:3111001 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3111001 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:3111001 | pubmed:volume | 46 | lld:pubmed |
| pubmed-article:3111001 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3111001 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3111001 | pubmed:pagination | 213-23 | lld:pubmed |
| pubmed-article:3111001 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:meshHeading | pubmed-meshheading:3111001-... | lld:pubmed |
| pubmed-article:3111001 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3111001 | pubmed:articleTitle | Measurement of tissue plasminogen activator in plasma. A comparison of 3 methods and description of a new improved technique. | lld:pubmed |
| pubmed-article:3111001 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3111001 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:3111001 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
