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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1987-8-12
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pubmed:abstractText |
The effect of mild acute exercise (swimming for 1 h), restraint for 1 h and fasting for 48 h on myocardial norepinephrine concentration was compared with rats "at rest" using 320 control and chronically T. cruzi-infected rats at 50, 110, 200 and 380 days of age. Ventricular norepinephrine concentrations of control and similarly aged T. cruzi-infected rats were different for 2 of 4 "at rest" groups. Significant and opposite differences in ventricular norepinephrine were observed for restrained T. cruzi-infected rats when compared to controls (-35% in 50-day old rats and +40% in 110-day old rats). Exercised, "at rest" and fasted control rats presented a significant age-dependent decrease of ventricular norepinephrine concentration, which was not observed for restrained control rats. Norepinephrine levels of pooled atria from 120-day old "at rest" T. cruzi-infected rats were significantly lower than those from non-infected controls, whereas no difference was found in serotonin levels. The lability of myocardial norepinephrine levels in T. cruzi-infected rats suggests, but does not demonstrate, that there is a disturbance of the cardiac sympathetic control.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0100-879X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
367-74
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:3109533-Animals,
pubmed-meshheading:3109533-Chagas Disease,
pubmed-meshheading:3109533-Food Deprivation,
pubmed-meshheading:3109533-Male,
pubmed-meshheading:3109533-Myocardium,
pubmed-meshheading:3109533-Norepinephrine,
pubmed-meshheading:3109533-Physical Exertion,
pubmed-meshheading:3109533-Rats,
pubmed-meshheading:3109533-Restraint, Physical,
pubmed-meshheading:3109533-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
Changes in myocardial norepinephrine levels in response to stress, exercise and aging in control and T. cruzi-infected rats.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|