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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions |
umls-concept:C0001899,
umls-concept:C0003241,
umls-concept:C0005768,
umls-concept:C0005795,
umls-concept:C0018821,
umls-concept:C0019158,
umls-concept:C0033522,
umls-concept:C0229671,
umls-concept:C0369330,
umls-concept:C0680730,
umls-concept:C1148554,
umls-concept:C1511790,
umls-concept:C1522609,
umls-concept:C1554112,
umls-concept:C2745955
|
| pubmed:issue |
6
|
| pubmed:dateCreated |
1987-7-14
|
| pubmed:abstractText |
We studied a group of 64 patients undergoing cardiac surgery for the occurrence of post-transfusion hepatitis during a follow-up period of 5 months. They received blood units (packed red cells in saline-adenine-glucose medium and/or fresh frozen plasma exclusively) from 447 volunteer donors. Post-transfusion hepatitis was identified in 5 patients: 1 patient had cytomegalovirus hepatitis and the remaining 4 cases were defined, by exclusion, as non-A, non-B hepatitis (with prevalence and incidence rates of 80% and 6.25% respectively). We found no statistically significant differences between the numbers of transfused blood product units in patients who developed non-A, non-B hepatitis as compared to those who did not. Our analysis of the predictive effectiveness of alanine aminotransferase and anti-HBc antibodies screening in blood donors to prevent non-A, non-B post-transfusion hepatitis led to the following conclusions: we failed to confirm the association between anti-HBc in blood donors and enhanced risk of non-A, non-B hepatitis in recipients since no case developed among patients receiving blood products from anti-HBc positive donors. So, 20 donors (4.5%) would have been discarded without any reduction of the incidence of non-A, non-B hepatitis. we could not confirm nor exclude the possibility that screening donor blood for elevated alanine aminotransferase levels would have reduced the number of non-A, non-B hepatitis in recipients.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0338-4535
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
485-94
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3108992-Adult,
pubmed-meshheading:3108992-Aged,
pubmed-meshheading:3108992-Alanine Transaminase,
pubmed-meshheading:3108992-Blood Donors,
pubmed-meshheading:3108992-Blood Transfusion,
pubmed-meshheading:3108992-Cardiac Surgical Procedures,
pubmed-meshheading:3108992-Clinical Enzyme Tests,
pubmed-meshheading:3108992-Evaluation Studies as Topic,
pubmed-meshheading:3108992-Female,
pubmed-meshheading:3108992-Follow-Up Studies,
pubmed-meshheading:3108992-Hepatitis, Viral, Human,
pubmed-meshheading:3108992-Hepatitis B Antibodies,
pubmed-meshheading:3108992-Hepatitis B Core Antigens,
pubmed-meshheading:3108992-Hepatitis C,
pubmed-meshheading:3108992-Humans,
pubmed-meshheading:3108992-Male,
pubmed-meshheading:3108992-Middle Aged,
pubmed-meshheading:3108992-Postoperative Period,
pubmed-meshheading:3108992-Prospective Studies
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
[Occurrence of non-A, non-B post-transfusion hepatitis in heart surgery. Prospective study on the value of the determination of serum alanine aminotransferase and detection of anti-HBc antibodies in blood donors].
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|